Article
Humoral immune response to epidermal growth factor receptor in lung cancer.
Immunologic research - 1 Feb 2021
Wang Yulin, Liu Fenghui, OuYang Songyun, Liu Man, Zhang Xue, Wang Peng, Zhao Chunling, Zhang Liguo, Dai Liping
Abstract excerpt
The aim of this study was to explore the potential value of autoantibody to epidermal growth factor receptor (EGFR) in the diagnosis of lung cancer (LC) and its relation with EGFR mutations. Enzyme-linked immunosorbent assay (ELISA) was performed to detect the level of autoantibody to EGFR in sera from 254 LC patients and 222 normal controls (NCs). Besides, the mRNA and protein levels of EGFR were investigated in...
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