Article
Cancer/testis antigen expression as a predictor for epidermal growth factor receptor mutation and prognosis in lung adenocarcinoma.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery - 1 Apr 2013
Baba Tetsuro, Shiota Hironobu, Kuroda Koji, Shigematsu Yoshiki, Ichiki Yoshinobu, Uramoto Hidetaka, Hanagiri Takeshi, Tanaka Fumihiro
Abstract excerpt
OBJECTIVES: Immune therapy targeting cancer/testis (CT) antigens improve the survival in several types of solid tumours. The expression of CT antigens is related to poor survival in non-small-cell lung cancer (NSCLC). The epidermal growth factor receptor (EGFR) mutation is the best predictive factor for the sensitivity to tyrosine kinase inhibitors in lung adenocarcinoma. The aim of this study was to elucidate...
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