Article
Monitoring of carcinoembryonic antigen levels is predictive of EGFR mutations and efficacy of EGFR-TKI in patients with lung adenocarcinoma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 May 2014
Zhang Yanwei, Jin Bo, Shao Minhua, Dong Yu, Lou Yuqing, Huang Aimi, Han Baohui
Abstract excerpt
For the detection of epidermal growth factor receptor (EGFR) mutations, tumor tissues may not always be available. Not all the patients harboring EGFR mutation have a clinical response after the treatment of epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKI). EGFR mutations were detected in 70 cases of newly diagnosed non-smoking adenocarcinoma, and patients harboring EGFR mutations received...
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