Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptional profiling of microglia in the injured brain reveals distinct molecular features underlying neurodegeneration

25 Jan 2021

Abstract excerpt

Neurotrauma has been recognized as a risk factor for neurodegenerative diseases, and sex difference of the incidence and outcome of neurodegenerative diseases has long been recognized. Past studies suggest that microglia could play a versatile role in both health and disease. So far, the microglial mechanisms underlying neurodegeneration and potentially lead to sex-specific therapies are still very open. Here we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Neuroinflammation and Neurodegeneration Mechanisms
Share to S100 Proteins and Annexins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33492723
DOI: 10.1002/glia.23966

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptional profiling of microglia in the injured brain reveals distinct molecular features underlying neurodegenerationPMID 33492723Read ↗

Single-cell RNA sequencing reveals time- and sex-specific responses of spinal cord microglia to peripheral nerve injury and links ApoE to neuropathic painSemantic proximity Read ↗

Sex-Specific Features of Microglia from Adult Mice.Semantic proximity Read ↗

Next generation transcriptomics and genomics elucidate biological complexity of microglia in health and diseaseSemantic proximity Read ↗

The Pathological Activation of Microglia Is Modulated by Sexually Dimorphic Pathways.Semantic proximity Read ↗

The proteomic landscape of microglia in health and diseaseSemantic proximity Read ↗

An overview of microglia ontogeny and maturation in the homeostatic and pathological brain.Semantic proximity Read ↗

Repopulated spinal cord microglia exhibit a unique transcriptome and contribute to pain resolutionSemantic proximity Read ↗

The meningeal transcriptional response to traumatic brain injury and agingSemantic proximity Read ↗

The transcriptional profile of microglia : from brain to dishSemantic proximity Read ↗

Sex-specific molecular and cellular phenotypes during resolution of neuropathic pain in dorsal root ganglia.Semantic proximity Read ↗

Integration of single-cell and bulk RNA sequencing data reveals key cell types and regulators in traumatic brain injurySemantic proximity Read ↗

The sexed retina: a combined single-cell and bulk RNA sequencing analysis of healthy aging human retinaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.