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Article

Chimeric lipoproteins for leptospirosis vaccine: immunogenicity and protective potential

22 Jul 2024

Abstract excerpt

Leptospirosis, a neglected zoonotic disease, is caused by pathogenic spirochetes belonging to the genus Leptospira and has one of the highest morbidity and mortality rates worldwide. Vaccination stands out as one of the most effective preventive measures for susceptible populations. Within the outer membrane of Leptospira spp., we find the LIC12287, LIC11711, and LIC13259 lipoproteins. These are of interest due...

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PMID: 39037584
DOI: 10.1007/s00253-024-13196-1

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