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Electrophysiological evaluation of human induced pluripotent stem cell-derived cardiomyocytes obtained by different methods

18 Jan 2021

Abstract excerpt

The human induced pluripotent stem cells (hiPSCs) derived cardiomyocytes (CMs) (hiPSC-CMs) retain the same genetic information as the donor, and they have been shown to faithfully recapitulate the disease phenotypes of various genetic cardiac diseases. The hiPSC-CMs can be utilized in multiple types of studies and in most cases, the functionality of hiPSC-CMs is of interest. For the functional analyses, the...

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PMID: 33485184
DOI: 10.1016/j.scr.2021.102176

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