Article
Adiponectin affects estimated glomerular filtration rate: A two-sample bidirectional Mendelian randomization study.
Nephrology (Carlton, Vic.) - 1 Mar 2021
Bai Yulan, Chen Zefeng, Wen Zheng, Long Xinyang, Mo Zengnan, Xu Jianfeng
Abstract excerpt
BACKGROUND: The causal relationship between adiponectin (ADPN) and estimated glomerular filtration rate (eGFR) is unclear. This study adopts a two-sample bidirectional Mendelian randomization (MR) study to explore the causal relationship between ADPN and eGFR. METHODS: Using eight single nucleotide polymorphisms (SNP) of ADPN and 26 SNP of eGFR as instrumental variables, the study performs a two-sample...
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