Article
Generation of an urine-derived induced pluripotent stem cell line WMUi017-A from a X-linked Renpenning syndrome (X-RSY) patient with the hemizygous PQBP1 gene mutation p.P609A (c.1825C>G).
Stem cell research - 1 Mar 2021
Guo Xiaoling, Zhang Xufei, Wang Linlin, He Lingyun, Ding Yinjuan, Chen Huihui, Wang Dexuan, Rong Xing, Shen Xian, Lin Jian, Chu Maoping
Abstract excerpt
The mutations of polyglutamine binding protein 1 gene (PQBP1) can lead to the rare inherited X-linked Renpenning syndrome (X-RSY). Here, an induced pluripotent stem cell (iPSC) line WMUi017-A was generated through reprogramming the urine cells of a 5-year-old male X-RSY patient with the hemizygous PQBP1 gene mutation p.P609A (c.1825C>G) using the commercial Sendai virus reprogramming system. The established iPSCs...
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