Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Piecing together the Pediatric Brain Tumor Puzzle.

Trends in genetics : TIG - 1 Mar 2021

Nör Carolina, Ramaswamy Vijay

Abstract excerpt

A recent study by Petralia et al. of 218 pediatric brain tumors across seven different entities applied an integrated approach incorporating proteomics, phosphoproteomics, whole-genome sequencing, and RNA sequencing. This elegant study unveiled new signaling pathways, the composition of tumor microenvironments, and functional effects of copy number variants and somatic mutations.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to DNA Copy Number Variations
Share to Neoplasm Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Pediatrics

Share to Proteomics

Share to Sequence Analysis, RNA

Share to Tumor Microenvironment

Share to Whole Genome Sequencing

Source

Identifiers

PMID: 33455817
DOI: 10.1016/j.tig.2021.01.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Piecing together the Pediatric Brain Tumor Puzzle.PMID 33455817Read ↗

Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer.Semantic proximity Read ↗

A living pediatric brain tumor atlas reveals histomolecular diversity and therapeutic vulnerabilities for precision neuro-oncologySemantic proximity Read ↗

Review of molecular classification and treatment implications of pediatric brain tumors.Semantic proximity Read ↗

Pediatric Brain TumorsSemantic proximity Read ↗

Molecular Heterogeneity and Cellular Diversity: Implications for Precision Treatment in MedulloblastomaSemantic proximity Read ↗

Improving Diagnostic and Therapeutic Outcomes in Pediatric Brain Tumors.Semantic proximity Read ↗

OpenPBTA: An Open Pediatric Brain Tumor AtlasSemantic proximity Read ↗

Genomic profiling in pediatric brain tumors.Semantic proximity Read ↗

Pediatric Brain Tumors: An Update.Semantic proximity Read ↗

Molecular biomarkers in pediatric glial tumors: a needed wind of change.Semantic proximity Read ↗

Review of the genomic landscape of common pediatric CNS tumors and how data sharing will continue to shape this landscape in the future.Semantic proximity Read ↗

The importance of escalating molecular diagnostics in patients with low-grade pediatric brain cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.