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Cancer Stem Cells and Nucleolin as Drivers of Carcinogenesis

13 Jan 2021

Abstract excerpt

Cancer, one of the most mortal diseases worldwide, is characterized by the gain of specific features and cellular heterogeneity. Clonal evolution is an established theory to explain heterogeneity, but the discovery of cancer stem cells expanded the concept to include the hierarchical growth and plasticity of cancer cells. The activation of epithelial-to-mesenchymal transition and its molecular players are widely...

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PMID: 33451077
DOI: 10.3390/ph14010060

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