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Preimplantation Genetic Testing for Aneuploidy – a Castle Built on Sand

13 Jan 2021

Abstract excerpt

Preimplantation genetic testing for aneuploidy (PGT-A) has become a routine add-on for in vitro fertilization (IVF) to determine whether human embryos are to be clinically utilized or disposed of. Studies claiming IVF outcome improvements following PGT-A, however, used highly selected patient populations or inappropriate statistical methodologies. PGT-A was never clinically validated in its ability to define a...

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PMID: 33446425
DOI: 10.1016/j.molmed.2020.11.009

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