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Preimplantation genetic testing for aneuploidy (PGT‐A): The biology, the technology and the clinical outcomes

27 Feb 2019

Abstract excerpt

Preimplantation genetic testing for aneuploidy (PGT-A) seeks to identify preimplantation embryos with a normal chromosome complement (euploid) during in vitro fertilisation (IVF). By sifting out embryos with abnormal chromosome numbers (aneuploid), PGT-A should theoretically improve pregnancy success. However, earlier versions of PGT-A were ineffective, and in some cases, detrimental, due to biopsy-induced trauma...

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PMID: 30811595
DOI: 10.1111/ajo.12960

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