Article
Very early onset eosinophilic esophagitis is common, responds to standard therapy, and demonstrates enrichment for CAPN14 genetic variants.
The Journal of allergy and clinical immunology - 1 Jan 2021
Lyles John L, Martin Lisa J, Shoda Tetsuo, Collins Margaret H, Trimarchi Michael P, He Hua, Kottyan Leah C, Mukkada Vincent A, Rothenberg Marc E
Abstract excerpt
BACKGROUND: Eosinophilic esophagitis (EoE) is a chronic, food antigen-mediated disease characterized by esophageal dysfunction and intraepithelial eosinophil accumulation. OBJECTIVE: We hypothesized that very early onset EoE (V-EoE) would be enriched for early-life and genetic factors and have worse presentation and prognosis than later-onset pediatric EoE (L-EoE). METHODS: We conducted a single-site,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.