Article
High-grade uterine sarcoma with osteosarcomatous differentiation arising from a MED12-mutated leiomyoma, a case report.
Pathology international - 1 Mar 2021
Le Minh-Khang, Omori Makiko, Oishi Naoki, Oi Megumi, Fukasawa Hiroko, Hirata Shuji, Kondo Tetsuo
Abstract excerpt
Uterine osteosarcoma has been reported, but it is an extremely rare tumor with highly aggressive behavior and poor prognosis. The pathogenesis of uterine osteosarcoma is not fully understood. Herein, we report on a high-grade uterine sarcoma with focal osteosarcomatous differentiation that developed from a long-standing MED12-mutated leiomyoma. A 47-year-old nulligravida woman, with known uterine leiomyoma...
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