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Article

Regulatory protein HilD stimulates Salmonella Typhimurium invasiveness by promoting smooth swimming via the methyl-accepting chemotaxis protein McpC.

Nature communications - 13 Jan 2021

Cooper Kendal G, Chong Audrey, Kari Laszlo, Jeffrey Brendan, Starr Tregei, Martens Craig, McClurg Molly, Posada Victoria R, Laughlin Richard C, Whitfield-Cargile Canaan, Garry Adams L, Bryan Laura K, Little Sara V, Krath Mary, Lawhon Sara D, Steele-Mortimer Olivia

Abstract excerpt

In the enteric pathogen Salmonella enterica serovar Typhimurium, invasion and motility are coordinated by the master regulator HilD, which induces expression of the type III secretion system 1 (T3SS1) and motility genes. Methyl-accepting chemotaxis proteins (MCPs) detect specific ligands and control the direction of the flagellar motor, promoting tumbling and changes in direction (if a repellent is detected) or...

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Identifiers

PMID: 33441540
DOI: 10.1038/s41467-020-20558-6
PMCID: PMC7806825

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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