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Article

Ceruloplasmin Deamidation in Neurodegeneration: From Loss to Gain of Function.

International journal of molecular sciences - 11 Jan 2021

Zanardi Alan, Alessio Massimo

Abstract excerpt

Neurodegenerative disorders can induce modifications of several proteins; one of which is ceruloplasmin (Cp), a ferroxidase enzyme found modified in the cerebrospinal fluid (CSF) of neurodegenerative diseases patients. Cp modifications are caused by the oxidation induced by the pathological environment and are usually associated with activity loss. Together with oxidation, deamidation of Cp was found in the CSF...

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Identifiers

PMID: 33440850
DOI: 10.3390/ijms22020663
PMCID: PMC7827708

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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