Assessment of Adenosine Triphosphatase Phospholipid Transporting 8B1 (ATP8B1) Function in Patients With Cholestasis With ATP8B1 Deficiency by Using Peripheral Blood Monocyte-Derived Macrophages.

doi:10.1002/hep4.1605

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Assessment of Adenosine Triphosphatase Phospholipid Transporting 8B1 (ATP8B1) Function in Patients With Cholestasis With ATP8B1 Deficiency by Using Peripheral Blood Monocyte-Derived Macrophages.

Hepatology communications - 1 Jan 2021

Mizutani Ayumu, Sabu Yusuke, Naoi Sotaro, Ito Shogo, Nakano Satoshi, Minowa Kei, Mizuochi Tatsuki, Ito Koichi, Abukawa Daiki, Kaji Shunsaku, Sasaki Mika, Muroya Koji, Azuma Yoshihiro, Watanabe Satoshi, Oya Yuki, Inomata Yukihiro, Fukuda Akinari, Kasahara Mureo, Inui Ayano, Takikawa Hajime, Kusuhara Hiroyuki, Bessho Kazuhiko, Suzuki Mitsuyoshi, Togawa Takao, Hayashi Hisamitsu

Abstract excerpt

Adenosine triphosphatase phospholipid transporting 8B1 (ATP8B1) deficiency, an ultrarare autosomal recessive liver disease, includes severe and mild clinical forms, referred to as progressive familial intrahepatic cholestasis type 1 (PFIC1) and benign recurrent intrahepatic cholestasis type 1 (BRIC1), respectively. There is currently no practical method for determining PFIC1 or BRIC1 at an early disease course...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphatases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antigens, CD

Share to Antigens, Differentiation, Myelomonocytic

Share to CD163 Antigen

Share to Cholestasis

Share to Interleukin-10

Share to Lipopolysaccharide Receptors

Share to Receptors, Cell Surface

Source

Open in PubMed Open full text

Identifiers

PMID: 33437900
DOI: 10.1002/hep4.1605
PMCID: PMC7789840

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Assessment of Adenosine Triphosphatase Phospholipid Transporting 8B1 (ATP8B1) Function in Patients With Cholestasis With ATP8B1 Deficiency by Using Peripheral Blood Monocyte-Derived Macrophages.PMID 33437900Read ↗

Assessment of ATP8B1 Deficiency in Pediatric Patients With Cholestasis Using Peripheral Blood Monocyte-Derived Macrophages.Semantic proximity Read ↗

Mutation Analysis and Disease Features at Presentation in a Multi-Center Cohort of Children With Monogenic Cholestasis.Semantic proximity Read ↗

The molecular landscape of progressive familial intrahepatic cholestasis in Turkey: Defining the molecular profiles and expanding the variant spectrum.Semantic proximity Read ↗

Novel ATP8B1 mutation in an adult male with progressive familial intrahepatic cholestasis.Semantic proximity Read ↗

Intrahepatic cholestasis in two omani siblings associated with a novel homozygous ATP8B1 mutation, c.379C>G (p.L127V).Semantic proximity Read ↗

Characterization of mutations in ATP8B1 associated with hereditary cholestasis.Semantic proximity Read ↗

Update on progressive familial intrahepatic cholestasis.Semantic proximity Read ↗

Functional analysis and transcriptomic profiling of iPSC-derived macrophages and their application in modeling Mendelian disease.Semantic proximity Read ↗

Clinical phenotype of adult-onset liver disease in patients with variants in ABCB4, ABCB11, and ATP8B1.Semantic proximity Read ↗

Folding Defects in P-Type Atp 8B1 Associated With Hereditary Cholestasis Are Ameliorated by 4-PhenylbutyrateSemantic proximity Read ↗

Diagnostic challenges in progressive familial intrahepatic cholestasis type 3 (PFIC3) misdiagnosed as Wilson's disease: A systematic review.Semantic proximity Read ↗

Benign recurrent intrahepatic cholestasis type 2 is caused by mutations in ABCB11Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.