Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations.

Communications biology - 12 Jan 2021

Panyard Daniel J, Kim Kyeong Mo, Darst Burcu F, Deming Yuetiva K, Zhong Xiaoyuan, Wu Yuchang, Kang Hyunseung, Carlsson Cynthia M, Johnson Sterling C, Asthana Sanjay, Engelman Corinne D, Lu Qiongshi

Abstract excerpt

The study of metabolomics and disease has enabled the discovery of new risk factors, diagnostic markers, and drug targets. For neurological and psychiatric phenotypes, the cerebrospinal fluid (CSF) is of particular importance. However, the CSF metabolome is difficult to study on a large scale due to the relative complexity of the procedure needed to collect the fluid. Here, we present a metabolome-wide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Brain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cerebrospinal Fluid

Share to Cognitive Dysfunction

Share to Cohort Studies

Share to Genome-Wide Association Study

Share to Metabolomics

Share to Quantitative Trait Loci

Source

Open in PubMed Open full text

Identifiers

PMID: 33437055
DOI: 10.1038/s42003-020-01583-z
PMCID: PMC7803963

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations.PMID 33437055Read ↗

Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associationsSemantic proximity Read ↗

Quantitative trait loci mapping of circulating metabolites in cerebrospinal fluid to uncover biological mechanisms involved in brain-related phenotypesSemantic proximity Read ↗

Quantitative trait loci mapping of circulating metabolites in cerebrospinal fluid to uncover biological mechanisms involved in brain-related phenotypes.Semantic proximity Read ↗

Genetic architecture of cerebrospinal fluid and brain metabolite levels and the genetic colocalization of metabolites with human traits.Semantic proximity Read ↗

Unique genetic architecture of CSF and brain metabolites pinpoints the novel targets for the traits of human wellnessSemantic proximity Read ↗

Multi-platform characterization of the human cerebrospinal fluid metabolome: a comprehensive and quantitative updateSemantic proximity Read ↗

CSF metabolites associated with biomarkers of Alzheimer’s disease pathologySemantic proximity Read ↗

Metabolomic epidemiology offers insights into disease aetiology.Semantic proximity Read ↗

CSF metabolites associated with biomarkers of Alzheimer’s disease pathologySemantic proximity Read ↗

Genetic atlas of plasma metabolome across 40 human common diseases: mapping causal metabolites to disease risk.Semantic proximity Read ↗

Evaluating metabolome-wide causal effects on risk for psychiatric and neurodegenerative disordersSemantic proximity Read ↗

Whole-Genome Sequencing Analysis of Human Metabolome in Multi-Ethnic Populations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.