Article
H2AK121ub in Arabidopsis associates with a less accessible chromatin state at transcriptional regulation hotspots.
Nature communications - 12 Jan 2021
Yin Xiaochang, Romero-Campero Francisco J, de Los Reyes Pedro, Yan Peng, Yang Jing, Tian Guangmei, Yang XiaoZeng, Mo Xiaorong, Zhao Shuangshuang, Calonje Myriam, Zhou Yue
Abstract excerpt
Although it is well established that the Polycomb Group (PcG) complexes maintain gene repression through the incorporation of H2AK121ub and H3K27me3, little is known about the effect of these modifications on chromatin accessibility, which is fundamental to understand PcG function. Here, by integrating chromatin accessibility, histone marks and expression analyses in different Arabidopsis PcG mutants, we show...
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