Article
Histone H2A variants confer specific properties to nucleosomes and impact on chromatin accessibility.
Nucleic acids research - 6 Sept 2018
Osakabe Akihisa, Lorkovic Zdravko J, Kobayashi Wataru, Tachiwana Hiroaki, Yelagandula Ramesh, Kurumizaka Hitoshi, Berger Frédéric
Abstract excerpt
In eukaryotes, variants of core histone H2A are selectively incorporated in distinct functional domains of chromatin and are distinguished by conserved sequences of their C-terminal tail, the L1 loop and the docking domain, suggesting that each variant confers specific properties to the nucleosome. Chromatin of flowering plants contains four types of H2A variants, which biochemical properties have not been...
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