Article
Step-Specific Adaptation and Trade-Off over the Course of an Infection by GASP Mutation Small Colony Variants.
mBio - 12 Jan 2021
Faucher Christian, Mazana Vincent, Kardacz Marion, Parthuisot Nathalie, Ferdy Jean-Baptiste, Duneau David
Abstract excerpt
During an infection, parasites face a succession of challenges, each decisive for disease outcome. The diversity of challenges requires a series of parasite adaptations to successfully multiply and transmit from host to host. Thus, the pathogen genotypes that succeed during one step might be counterselected in later stages of the infection. Using the bacterium Xenorhabdus nematophila and adult Drosophila...
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