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Article

A single promoter inversion switches Photorhabdus between pathogenic and mutualistic states.

Science (New York, N.Y.) - 6 Jul 2012

Somvanshi Vishal S, Sloup Rudolph E, Crawford Jason M, Martin Alexander R, Heidt Anthony J, Kim Kwi-suk, Clardy Jon, Ciche Todd A

Abstract excerpt

Microbial populations stochastically generate variants with strikingly different properties, such as virulence or avirulence and antibiotic tolerance or sensitivity. Photorhabdus luminescens bacteria have a variable life history in which they alternate between pathogens to a wide variety of insects and mutualists to their specific host nematodes. Here, we show that the P. luminescens pathogenic variant (P form)...

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Identifiers

PMID: 22767929
DOI: 10.1126/science.1216641
PMCID: PMC4006969

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Source receipt: pubmed, retrieved 7 Sept 2026.

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