Article
Capsid assembly is regulated by amino acid residues asparagine 47 and 48 in the VP2 protein of porcine parvovirus.
Veterinary microbiology - 1 Feb 2021
Wang Jucai, Liu Yunchao, Chen Yumei, Zhang Teng, Wang Aiping, Wei Qiang, Liu Dongmin, Wang Fangyu, Zhang Gaiping
Abstract excerpt
Porcine parvovirus (PPV) is a major cause of reproductive failure in swine and has caused substantial losses throughout the world. Viral protein 2 (VP2) of PPV is a major structural protein that can self-assemble into virus-like particles (VLP) with hemagglutination (HA) activity. In order to identify the essential residues involved in the mechanism of capsid assembly and to further understand the function of HA,...
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