Article

PCV Cap proteins fused with calreticulin expressed into polymers in Escherichia coli with high immunogenicity in mice

2020-03-26

Abstract excerpt

<h4>Background: </h4> ： Porcine circovirus type 2 (PCV2) is considered as one of the critical viral pathogens of porcine circovirus diseases (PCVDs), which results in economic losses in the pig breeding industry. Capsid protein (Cap) of PCV2 acts as the most protective antigen in the course of immune response. Therefore, developing a novel and safe subunit vaccine against PCV2 infection is needed. <h4>Results: </h...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a79f4b1a-1fa9-573e-9c46-2a342e35b13e
DOI: 10.21203/rs.3.rs-15890/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

PCV Cap proteins fused with calreticulin expressed into polymers in Escherichia coli with high immunogenicity in miceDOI 10.21203/rs.3.rs-15890/v2Read

Immunogenicity and Immunoprotection of PCV2 Virus-like Particles Incorporating Dominant T and B Cell Antigenic Epitopes Paired with CD154 Molecules in Piglets and MiceSemantic proximity Read

Self-assembly of virus-like particles of porcine circovirus type 2 capsid protein expressed from Escherichia coliSemantic proximity Read

Displaying epitope B and epitope 7 of porcine reproductive and respiratory syndrome virus on virus like particles of porcine circovirus type 2 provides partial protection to pigsSemantic proximity Read

Structure, Antigenic Properties, and Highly Efficient Assembly of PCV4 Capsid ProteinSemantic proximity Read

The Carboxyl Terminus of the Porcine Circovirus Type 2 Capsid Protein Is Critical to Virus-Like Particle Assembly, Cell Entry, and PropagationSemantic proximity Read

Engineering a bivalent nanoparticle vaccine with PCV2 capsid protein and PRRSV epitopesSemantic proximity Read

Identification of a Conserved B-Cell Epitope on the Capsid Protein of Porcine Circovirus Type 4Semantic proximity Read

Structural roles of PCV2 capsid protein N-terminus in PCV2 particle assembly and identification of PCV2 type-specific neutralizing epitopeSemantic proximity Read

Identification of a conserved B-cell epitope on the capsid protein of porcine circovirus type 4Semantic proximity Read

Large-scale Production of Novel Porcine Circovirus Type 2d (PCV2d) Subunit Vaccine Using E. coli PlatformSemantic proximity Read

Identification of a New Antigen Epitope in the Nuclear Localization Signal Region of Porcine Circovirus Type 2 Capsid ProteinSemantic proximity Read

Identification and Functional Analysis of the Novel ORF4 Protein Encoded by Porcine Circovirus Type 2Semantic proximity Read