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Article

Longitudinal analysis of cell-free mutated KRAS and CA 19-9 predicts survival following curative resection of pancreatic cancer.

BMC cancer - 11 Jan 2021

Hussung Saskia, Akhoundova Dilara, Hipp Julian, Follo Marie, Klar Rhena F U, Philipp Ulrike, Scherer Florian, von Bubnoff Nikolas, Duyster Justus, Boerries Melanie, Wittel Uwe, Fritsch Ralph M

Abstract excerpt

BACKGROUND: Novel biomarkers and molecular monitoring tools hold potential to improve outcome for patients following resection of pancreatic ductal adenocarcinoma (PDAC). We hypothesized that the combined longitudinal analysis of mutated cell-free plasma KRAS (cfKRASmut) and CA 19-9 during adjuvant treatment and follow-up might more accurately predict disease course than hitherto available parameters. METHODS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33430810
DOI: 10.1186/s12885-020-07736-x
PMCID: PMC7802224

Genes

KRAS

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