Article
Establishing a novel colorectal cancer predictive model based on unique gut microbial single nucleotide variant markers.
Gut microbes - 1 Jan 2000
Ma Chenchen, Chen Kaining, Wang Yuanyuan, Cen Chaoping, Zhai Qixiao, Zhang Jiachao
Abstract excerpt
Current metagenomic species-based colorectal cancer (CRC) microbial biomarkers may confuse diagnosis because the genetic content of different microbial strains, even those belonging to the same species, may differ from 5% to 30%. Here, a total of 7549 non-redundant single nucleotide variants (SNVs) were annotated in 25 species from 3 CRC cohorts (n = 249). Then, 22 microbial SNV markers that contributed to...
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