Article
Breast cancer risk after age 60 among BRCA1 and BRCA2 mutation carriers.
Breast cancer research and treatment - 1 Jun 2021
Stjepanovic Neda, Lubinski Jan, Moller Pal, Randall Armel Susan, Foulkes William D, Tung Nadine, Neuhausen Susan L, Kotsopoulos Joanne, Sun Ping, Sun Sophie, Eisen Andrea, Narod Steven A
Abstract excerpt
PURPOSE: It is not known whether the risk of breast cancer among BRCA1 and BRCA2 mutation carriers after age 60 is high enough to justify intensive screening or prophylactic surgery. Thus, we conducted a prospective analysis of breast cancer risk in BRCA1 and BRCA2 mutation carriers from age 60 until age 80. METHODS: Subjects had no history of cancer and both breasts intact at age 60 (n = 699). Women were...
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