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Persistent accelerated epigenetic ageing in a longitudinal cohort of vertically infected HIV-positive adolescents

13 May 2023

Abstract excerpt

We have previously shown accelerated ageing in adolescents perinatally infected with HIV (PHIV +), based on discrepancies between epigenetic and chronological age. The current study examines follow-up longitudinal patterns of epigenetic ageing and the association of epigenetic ageing with cognition as well as whole brain structure changes in PHIV + and healthy controls enrolled in the Cape Town Adolescent...

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PMID: 37179258
DOI: 10.1007/s13365-023-01130-6

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