Article
hTERT genetic variation in depression.
Journal of affective disorders - 1 Jan 2016
Wei Ya Bin, Martinsson Lina, Liu Jia Jia, Forsell Yvonne, Schalling Martin, Backlund Lena, Lavebratt Catharina
Abstract excerpt
BACKGROUND: Telomeres are protective DNA-protein complexes forming the chromosome ends. TL differs between tissues. Shorter telomere length (TL) in blood leukocytes (LTL) has been associated with major depression, and with previous exposure to childhood adversity. TL studies on non-invasively sampled salivary DNA are less common. Telomerase, with its catalytic subunit hTERT, counteracts telomere shortening....
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