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Article

HER2 overexpression triggers the IL-8 to promote arsenic-induced EMT and stem cell-like phenotypes in human bladder epithelial cells.

Ecotoxicology and environmental safety - 15 Jan 2021

Zhou Qing, Jin Peiyu, Liu Jieyu, Li Sihao, Liu Weijue, Xi Shuhua

Abstract excerpt

Arsenic is a natural chemical element that is strongly associated with bladder cancer. Understanding the underlying mechanisms behind the association between arsenic and bladder cancer as well as identifying effective preventive interventions will help reduce the incidence and mortality of this disease. The epithelial-mesenchymal transition (EMT) and cancer stem cell (CSC) properties play key roles in cancer...

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Identifiers

PMID: 33396024
DOI: 10.1016/j.ecoenv.2020.111693

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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