Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants in NKG2D axis and susceptibility to Epstein-Barr virus-induced nasopharyngeal carcinoma.

Journal of cancer research and clinical oncology - 1 Mar 2021

Viet Nguyen Hoang, Trung Nguyen Quang, Dong Le Thanh, Trung Ly Quoc, Espinoza J Luis

Abstract excerpt

BACKGROUND: Nasopharyngeal carcinoma (NPC) is a rare epithelial carcinoma arising from the nasopharyngeal region. The pathogenesis of NPC is linked to Epstein-Barr virus (EBV) infection, although genetics and lifestyle factors appears to be also implicated. NKG2D is an immunoreceptor expressed by NK and T-cell subsets that recognizes MICA protein and other ligands on tumor cells. NKG2D interaction with MICA plays...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA, Viral
Share to Epstein-Barr Virus Infections

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Herpesvirus 4, Human

Share to Histocompatibility Antigens Class I

Share to Killer Cells, Natural

Share to Nasopharyngeal Carcinoma

Share to Nasopharyngeal Neoplasms

Share to NK Cell Lectin-Like Receptor Subfamily K

Source

Identifiers

PMID: 33392659
DOI: 10.1007/s00432-020-03475-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants in NKG2D axis and susceptibility to Epstein-Barr virus-induced nasopharyngeal carcinoma.PMID 33392659Read ↗

A functional polymorphism in the NKG2D gene modulates NK-cell cytotoxicity and is associated with susceptibility to Human Papilloma Virus-related cancers.Semantic proximity Read ↗

Genetic risk of extranodal natural killer T-cell lymphoma: a genome-wide association study.Semantic proximity Read ↗

Impact of toll-like receptor 4 variations on nasopharyngeal carcinoma risk and survival in tunisian population.Semantic proximity Read ↗

Genetic predisposition factors and nasopharyngeal carcinoma risk: a review of epidemiological association studies, 2000-2011: Rosetta Stone for NPC: genetics, viral infection, and other environmental factors.Semantic proximity Read ↗

Genetic polymorphisms in host innate immune sensor genes and the risk of nasopharyngeal carcinoma in North Africa.Semantic proximity Read ↗

Genetic risk of extranodal natural killer T-cell lymphoma: a genome-wide association study in multiple populations.Semantic proximity Read ↗

The interplay of host genetic factors and Epstein-Barr virus in the development of nasopharyngeal carcinoma.Semantic proximity Read ↗

Variation of the killer cell immunoglobulin-like receptors and HLA-C genes in nasopharyngeal carcinoma.Semantic proximity Read ↗

Human Leukocyte Antigens and Epstein–Barr Virus-Associated Nasopharyngeal Carcinoma: Old Associations Offer New Clues into the Role of Immunity in Infection-Associated CancersSemantic proximity Read ↗

MICA SNPs and the NKG2D system in virus-induced HCC.Semantic proximity Read ↗

A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci.Semantic proximity Read ↗

A single nucleotide polymorphism in the Epstein-Barr virus genome is strongly associated with a high risk of nasopharyngeal carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.