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Article

White matter microstructure across brain-based biotypes for psychosis - findings from the bipolar-schizophrenia network for intermediate phenotypes.

Psychiatry research. Neuroimaging - 28 Feb 2021

Kelly Sinead, Guimond Synthia, Pasternak Ofer, Lutz Olivia, Lizano Paulo, Cetin-Karayumak Suheyla, Sweeney John A, Pearlson Godfrey, Clementz Brett A, McDowell Jennifer E, Tamminga Carol A, Shenton Martha E, Keshavan Matcheri S

Abstract excerpt

The B-SNIP consortium identified three brain-based Biotypes across the psychosis spectrum, independent of clinical phenomenology. To externally validate the Biotype model, we used free-water fractional volume (FW) and free-water corrected fractional anisotropy (FAT) to compare white matter differences across Biotypes and clinical diagnoses. Diffusion tensor imaging data from 167 individuals were included: 41...

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PMID: 33385763
DOI: 10.1016/j.pscychresns.2020.111234

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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