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Article

Functionally non-redundant paralogs spe-47 and spe-50 encode FB-MO associated proteins and interact with him-8.

PloS one - 1 Jan 2020

Clark Jessica N, Prajapati Gaurav, Aldaco Fermina K, Sokolich Thomas J, Keung Steven S, Austin Sarojani P, Valdés Ángel A, LaMunyon Craig W

Abstract excerpt

The activation of C. elegans spermatids to crawling spermatozoa is affected by a number of genes including spe-47. Here, we investigate a paralog to spe-47: spe-50, which has a highly conserved sequence and expression, but which is not functionally redundant to spe-47. Phylogenetic analysis indicates that the duplication event that produced the paralogs occurred prior to the radiation of the Caenorhabditis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33382704
DOI: 10.1371/journal.pone.0230939
PMCID: PMC7774929

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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