Article
Pyruvate Kinase M2 Knockdown Suppresses Migration, Invasion, and Epithelial-Mesenchymal Transition of Gastric Carcinoma via Hypoxia-Inducible Factor Alpha/B-Cell Lymphoma 6 Pathway.
BioMed research international - 1 Jan 2020
Li Ning, Meng Dandan, Xu Yue, Gao Ling, Shen Fengqian, Tie Xiaojing, Zhang Yan, Yi Zhenying, Shen Wenjie, Liu Zonglan, Xu Zhiqiao
Abstract excerpt
Gastric carcinoma is a common malignant cancer. Pyruvate kinase M2 (PKM2) is highly expressed in cancers, including gastric carcinoma. However, its function and molecular mechanism in gastric carcinoma remains unclear. Here, we aimed to explore the function and the underlying mechanism of PKM2 on malignant phenotypes in gastric carcinoma. In this study, the mRNA levels and protein levels of PKM2 in gastric...
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