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MYBL2 promotes cell proliferation and inhibits cell apoptosis via PI3K/AKT and BCL2/BAX/Cleaved-caspase-3 signaling pathway in gastric cancer cells

17 Mar 2025

Abstract excerpt

The transcription factor MYB proto-oncogene like 2 (MYBL2) has been reported to be involved in the occurrence and development of various tumors, however, its role in gastric cancer (GC) remains to be elucidated. In this study, the Kaplan-Meier plotter was used to evaluate the prognostic value of different MYBL2 expression levels in GC patients. The UALCAN database were applied to analyze the relationships between...

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Cancer Mechanisms and Therapy
Cancer-related Molecular Pathways
PI3K/AKT/mTOR signaling in cancer

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40097530
DOI: 10.1038/s41598-025-93022-4

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