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Article

Causal Relationship between Adiponectin and Diabetic Retinopathy: A Mendelian Randomization Study in an Asian Population.

Genes - 24 Dec 2020

Huang Yu-Chuen, Chang Ya-Wen, Cheng Chun-Wen, Wu Chia-Ming, Liao Wen-Ling, Tsai Fuu-Jen

Abstract excerpt

Adiponectin (APN) is suggested to be a potential biomarker for predicting diabetic retinopathy (DR) risk, but the association between APN and DR has been inconsistent in observational studies. We used a Mendelian randomization (MR) analysis to evaluate if circulating APN levels result in DR. We applied three different genetic risk scores (GRS): GRSAll combined all 47 single nucleotide polymorphisms (SNPs), which...

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Identifiers

PMID: 33374471
DOI: 10.3390/genes12010017
PMCID: PMC7823606

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