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Article

A Prognostic Molecular Signature of N⁶-Methyladenosine Methylation Regulators for Soft-Tissue Sarcoma from The Cancer Genome Atlas Database.

Medical science monitor : international medical journal of experimental and clinical research - 28 Dec 2020

Hou Mingming, Guo Xiaohui, Chen Yu, Cong Lidan, Pan Changwu

Abstract excerpt

BACKGROUND Soft-tissue sarcomas are a group of heterogeneous and rare mesenchymal tumors with aggressive behavior. We aimed to identify the molecular signatures of N⁶-methyladenosine (m6A) methylation regulators associated with patient prognosis using The Cancer Genome Atlas (TCGA) database. MATERIAL AND METHODS To evaluate the role of m⁶A in soft-tissue sarcomas, genomic and clinical data were downloaded from...

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Adenosine
Databases, Genetic
Disease-Free Survival
DNA Copy Number Variations
DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Multivariate Analysis

Proportional Hazards Models

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Identifiers

PMID: 33370249
DOI: 10.12659/MSM.928400
PMCID: PMC7780893

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