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Article

The CTGF gene -945 G/C polymorphism is associated with target lesion revascularization for in-stent restenosis.

Experimental and molecular pathology - 1 Feb 2021

Bujak Kamil, Lejawa Mateusz, Gąsior Mariusz, Osadnik Tadeusz

Abstract excerpt

BACKGROUND AND AIMS: Previous studies have shown that transforming growth factor β (TGF-β) and vascular endothelial growth factor A (VEGF-A) pathways are involved in the in-stent restenosis (ISR) process. The present study aimed to assess the relationship between single-nucleotide polymorphisms (SNPs) in genes encoding downstream proteins of TGF-β and VEGF-A pathways and the risk of target lesion...

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PMID: 33358742
DOI: 10.1016/j.yexmp.2020.104598

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