Article
Tumor necrosis factor-alpha plays an important role in restenosis development.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Dec 2005
Monraats Pascalle S, Pires Nuno M M, Schepers Abbey, Agema Willem R P, Boesten Lianne S M, de Vries Margreet R, Zwinderman Aeilko H, de Maat Moniek P M, Doevendans Pieter A F M, de Winter Robbert J, Tio René A, Waltenberger Johannes, 't Hart Leen M, Frants Rune R, Quax Paul H A, van Vlijmen Bart J M, Havekes Louis M, van der Laarse Arnoud, van der Wall Ernst E, Jukema J Wouter
Abstract excerpt
Genetic factors appear to be important in the restenotic process after percutaneous coronary intervention (PCI), as well as in inflammation, a pivotal factor in restenosis. TNFalpha, a key regulator of inflammatory responses, may exert critical influence on the development of restenosis after PCI. The GENetic DEterminants of Restenosis (GENDER) project included 3104 patients who underwent a successful PCI....
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