Article
Functional polymorphism rs710218 in the gene coding GLUT1 protein is associated with in-stent restenosis.
Biomarkers in medicine - 1 Jan 2015
Osadnik Tadeusz, Strzelczyk Joanna, Bujak Kamil, Reguła Rafał, Wasilewski Jarosław, Fronczek Martyna, Kurek Anna, Gawlita Marcin, Gonera Małgorzata, Gierlotka Marek, Lekston Andrzej, Hawranek Michał, Myrda Krzysztof, Wiczkowski Andrzej, Ostrowska Zofia, Gąsior Mariusz, Poloński Lech
Abstract excerpt
AIM: To analyze the association between in-stent restenosis (ISR) and polymorphisms in genes coding IGF-1, IGFBP3, ITGB3 and GLUT1, which play an important role in the smooth muscle cell proliferation and extracellular matrix synthesis - the main components of neointima. MATERIALS & METHODS: We analyzed 265 patients who underwent bare metal stent implantation. RESULTS: The differences in the occurrence of ISR...
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