Article
The Calcium-Sensing Receptor Is Essential for Calcium and Bicarbonate Sensitivity in Human Spermatozoa.
The Journal of clinical endocrinology and metabolism - 25 Mar 2021
Boisen Ida Marie, Rehfeld Anders, Mos Iris, Poulsen Nadia Nicholine, Nielsen John Erik, Schwarz Peter, Rejnmark Lars, Dissing Steen, Bach-Mortensen Pernille, Juul Anders, Bräuner-Osborne Hans, Lanske Beate, Blomberg Jensen Martin
Abstract excerpt
CONTEXT: The calcium-sensing receptor (CaSR) is essential to maintain a stable calcium concentration in serum. Spermatozoa are exposed to immense changes in concentrations of CaSR ligands such as calcium, magnesium, and spermine during epididymal maturation, in the ejaculate, and in the female reproductive environment. However, the role of CaSR in human spermatozoa is unknown. OBJECTIVE: This work aimed to...
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