Protein engineering of alcohol dehydrogenase--1. Effects of two amino acid changes in the active site of yeast ADH-1.

doi:10.1093/protein/1.1.55

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Article

Protein engineering of alcohol dehydrogenase--1. Effects of two amino acid changes in the active site of yeast ADH-1.

Protein engineering - 1 Jan 2000

Murali C, Creaser E H

Abstract excerpt

One of the promises held out by protein engineering is the ability to alter predictably the properties of an enzyme to enable it to find new substrates or catalyse existing substrates more efficiently, such manipulations being of interest both enzymologically and, potentially, industrially. It ha...

Topics

Alcohol Dehydrogenase
Amino Acid Sequence
Base Sequence
Binding Sites
Genes, Fungal
Kinetics
Molecular Sequence Data
Mutation
Protein Engineering
Saccharomyces cerevisiae

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