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Article

An attempt to transform class characteristics within the alcohol dehydrogenase family.

FEBS letters - 25 Sept 1998

Hedberg J J, Strömberg P, Höög J O

Abstract excerpt

Human class I alcohol dehydrogenase was mutated at positions 57 and 115, exchanging for Asp and Arg respectively, in an attempt to introduce glutathione-dependent formaldehyde dehydrogenase characteristics. In addition, class III alcohol dehydrogenase, identical to glutathione-dependent formaldehyde dehydrogenase, was mutated at position 115, introducing Ser or Lys. The attempted class transformation was partly...

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PMID: 9771895
DOI: 10.1016/s0014-5793(98)01100-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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