Article
An attempt to transform class characteristics within the alcohol dehydrogenase family.
FEBS letters - 25 Sept 1998
Hedberg J J, Strömberg P, Höög J O
Abstract excerpt
Human class I alcohol dehydrogenase was mutated at positions 57 and 115, exchanging for Asp and Arg respectively, in an attempt to introduce glutathione-dependent formaldehyde dehydrogenase characteristics. In addition, class III alcohol dehydrogenase, identical to glutathione-dependent formaldeh...
Topics
- Alcohol Dehydrogenase
- Aldehyde Oxidoreductases
- Arginine
- Binding Sites
- Glutathione
- Humans
- Immunoblotting
- Kinetics
- Lauric Acids
- Leucine
- Lysine
- Mutation
- Recombinant Proteins
- Serine