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Article

Single-cell analysis supports a luminal-neuroendocrine transdifferentiation in human prostate cancer

16 Dec 2020

Abstract excerpt

Neuroendocrine prostate cancer is one of the most aggressive subtypes of prostate tumor. Although much progress has been made in understanding the development of neuroendocrine prostate cancer, the cellular architecture associated with neuroendocrine differentiation in human prostate cancer remain incompletely understood. Here, we use single-cell RNA sequencing to profile the transcriptomes of 21,292 cells from...

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PMID: 33328604
DOI: 10.1038/s42003-020-01476-1

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