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Identification of a Novel Mutation in B Allele in a Chinese Individual.

Clinical laboratory - 1 Nov 2024

Wang Haijuan, Zhao Hong, Chen Jian, Feng Jing, Ou Guojin

Abstract excerpt

BACKGROUND: There are 49 B alleles in the ISBT ABO blood group list. This study will describe a new missense mutation, c.784G>T, in exon 7 of the ABO in a Chinese individual. METHODS: A weak B was analyzed by serologic techniques. Exons 6 and 7 were sequenced directly through polymerase chain reaction-based typing (PCR-SBT). Subsequently, the heterozygous mutation sites in exon 7 were determined through cloning...

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PMID: 39506573
DOI: 10.7754/Clin.Lab.2024.240602

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