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Article

Using INFERNO to Infer the Molecular Mechanisms Underlying Noncoding Genetic Associations.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021

Amlie-Wolf Alexandre, Kuksa Pavel P, Lee Chien-Yueh, Mlynarski Elisabeth, Leung Yuk Yee, Wang Li-San

Abstract excerpt

The INFERNO method provides an integrative computational framework for characterizing the causal variants, tissue contexts, affected regulatory mechanisms, and target genes underlying noncoding genetic variants associated with any phenotype or disease of interest. Here we describe the computational steps required to run the full INFERNO pipeline on any dataset of interest.

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PMID: 33326071
DOI: 10.1007/978-1-0716-1158-6_6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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