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Article

Distinct genomic profiles of gestational choriocarcinoma, a unique cancer of pregnant tissues.

Experimental & molecular medicine - 1 Dec 2020

Jung Seung-Hyun, Choi Youn Jin, Kim Min Sung, Park Hyeon-Chun, Han Mi-Ryung, Hur Soo Young, Lee Ah Won, Shin Ok Ran, Kim Jeana, Lee Sung Hak, Hong Dongwan, Song Sang Yong, Chung Yeun-Jun, Lee Sug Hyung

Abstract excerpt

Little is known about genomic alterations of gestational choriocarcinoma (GC), unique cancer that originates in pregnant tissues, and the progression mechanisms from the nonmalignant complete hydatidiform mole (CHM) to GC. Whole-exome sequencing (20 GCs) and/or single-nucleotide polymorphism microarray (29 GCs) were performed. We analyzed copy-neutral loss-of-heterozygosity (CN-LOH) in 29 GCs that exhibited...

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Identifiers

PMID: 33319857
DOI: 10.1038/s12276-020-00544-0
PMCID: PMC8080714

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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