Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

U-RT1 - A new model for Richter transformation.

Neoplasia (New York, N.Y.) - 1 Jan 2021

Schmid Teresa, Maier Julia, Martin Melanie, Tasdogan Alpaslan, Tausch Eugen, Barth Thomas F E, Stilgenbauer Stephan, Bloehdorn Johannes, Möller Peter, Mellert Kevin

Abstract excerpt

The advent of highly effective treatments targeting the disease biology of chronic lymphocytic leukemia (CLL) has transformed the therapeutic field tremendously. However, transformation into an aggressive B-cell lymphoma, called Richter syndrome (RS), remains highly challenging since the treatment options for this condition are still insufficient. Exploratory drug testing and experimental studies are restricted...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis
Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Comparative Genomic Hybridization

Share to Disease Progression

Share to In Situ Hybridization, Fluorescence

Share to Karyotype

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Primary Cell Culture

Source

Open in PubMed Open full text

Identifiers

PMID: 33316538
DOI: 10.1016/j.neo.2020.11.010
PMCID: PMC7736907

Genes

CDKN2A
NOTCH1
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

U-RT1 - A new model for Richter transformation.PMID 33316538Read ↗

Richter Transformation in Chronic Lymphocytic Leukemia: Update in the Era of Novel AgentsSemantic proximity Read ↗

Advances in the understanding of molecular genetics and therapy of Richter transformation in chronic lymphocytic leukemia.Semantic proximity Read ↗

Richter syndrome in chronic lymphocytic leukemia: updates on biology, clinical features and therapySemantic proximity Read ↗

Richter's syndrome: Novel and promising therapeutic alternatives.Semantic proximity Read ↗

Richter syndrome: molecular insights and clinical perspectivesSemantic proximity Read ↗

Chronic lymphocytic leukemia patient-derived xenografts recapitulate clonal evolution to Richter transformationSemantic proximity Read ↗

Richter’s transformation in patients with chronic lymphocytic leukaemia: a Nationwide Epidemiological StudySemantic proximity Read ↗

Richter's transformation in chronic lymphocytic leukemia.Semantic proximity Read ↗

Detection of early seeding of Richter transformation in chronic lymphocytic leukemiaSemantic proximity Read ↗

Richter transformation in chronic lymphocytic leukemia (CLL)-a pooled analysis of German CLL Study Group (GCLLSG) front line treatment trials.Semantic proximity Read ↗

Richter syndromeSemantic proximity Read ↗

Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.