Article
Richter transformation in chronic lymphocytic leukemia (CLL)-a pooled analysis of German CLL Study Group (GCLLSG) front line treatment trials.
Leukemia - 1 Jan 2021
Al-Sawaf O, Robrecht S, Bahlo J, Fink A M, Cramer P, V Tresckow J, Lange E, Kiehl M, Dreyling M, Ritgen M, Dürig J, Tausch E, Schneider C, Stilgenbauer S, Wendtner C M, Fischer K, Goede, Hallek M, Eichhorst B
Abstract excerpt
Richter transformation (RT) is defined as development of aggressive lymphoma in patients (pts) with CLL. The incidence rates of RT among pts with CLL range from 2 to 10%. The aim of this analysis is to report the frequency, characteristics and outcomes of pts with RT enrolled in trials of the GCLLSG. A total of 2975 pts with advanced CLL were reviewed for incidence of RT. Clinical, laboratory, and genetic data...
Topics
- Adult
- Aged
- Aged, 80 and over
- Biopsy
- Cell Transformation, Neoplastic
- Disease Progression
- Female
- Genetic Variation
- Germany
- Humans