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Article

A prospective study to explore the relationship between MTHFR C677T genotype, physiological folate levels, and postpartum psychopathology in at-risk women.

PloS one - 1 Jan 2020

Morris Emily, Hippman Catriona, Albert Arianne, Slomp Caitlin, Inglis Angela, Carrion Prescilla, Batallones Rolan, Andrighetti Heather, Ross Colin, Dyer Roger, Honer William, Austin Jehannine

Abstract excerpt

BACKGROUND: The etiology of postpartum psychopathologies are not well understood, but folate metabolism pathways are of potential interest. Demands for folate increase dramatically during pregnancy, low folate level has been associated with psychiatric disorders, and supplementation may improve symptomatology. The MTHFR C677T variant influences folate metabolism and has been implicated in depression during...

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Identifiers

PMID: 33315905
DOI: 10.1371/journal.pone.0243936
PMCID: PMC7735580

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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